Why the study?
Recent studies have reported favorable outcomes, including reduced mortality, among smokers after AMI (the smoker's paradox), prompting evaluation of smoking's true impact on clinical outcomes in AMI patients undergoing PCI.
Does current smoking worsen long-term clinical outcomes and increase lung cancer risk in patients with acute myocardial infarction undergoing PCI?
Population
10,683 AMI patients undergoing PCI
Comparison
Current smokers vs nonsmokers
Design
Propensity-score matched observational study
Follow-up
5 years
Authors
Loading...
Smoking may worsen adjusted post-AMI PCI outcomes; leaves open whether cessation improves prognosis in this population.
Does current smoking worsen long-term clinical outcomes and increase lung cancer risk in patients with acute myocardial infarction undergoing PCI?
The apparent 'smoker's paradox' in AMI patients is driven by confounding factors; after adjustment, smoking significantly increases the risk of MACE, cardiac death, and lung cancer.
Lee et al. (2021) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: