Good evidence to support a recommendation against use Quality of evidence 1 Evidence from 1 properly randomized, controlled trial 2 Evidence from 1 well-designed clinical trial, without randomization; from cohort or case-controlled analytic studies (preferably from 11 center); from multiple time-series; or from dramatic results from uncontrolled experiments 3 Evidence from opinions of respected authorities, based on clinical experience, descriptive studies, or reports of expert committees
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Pappas et al. (2004) studied this question.
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