Long-Term Outcomes in Patients With Type 2 Myocardial Infarction and Myocardial Injury
Key result
Type 2 myocardial infarction and myocardial injury were associated with higher 5-year all-cause death rates (62.5% and 72.4%, respectively) compared with type 1 myocardial infarction (36.7%).
Why the study?
Does type 2 myocardial infarction or myocardial injury increase long-term all-cause death compared to type 1 myocardial infarction in patients with elevated cardiac troponin?
Population
2,122 consecutive patients with elevated cardiac troponin I concentrations at a tertiary cardiac center…
Comparison
Type 2 myocardial infarction or myocardial injury vs Type 1 myocardial infarction
Design
Cohort
Follow-up
5 years
Authors
Discussion
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Member takes
Implication
High mortality after type 2 MI or injury warrants noncardiac evaluation; extends prior observations but leaves optimal strategies open.
Study Design
Type
Cohort (n=2,122)
Multicenter
No
Structured PICO
Does type 2 myocardial infarction or myocardial injury increase long-term all-cause death compared to type 1 myocardial infarction in patients with elevated cardiac troponin?
P
Population
2,122 consecutive patients with elevated cardiac troponin I concentrations (≥0.05 µg/L) evaluated at a tertiary cardiac center, followed for 5 years.
E
Exposure
Type 2 myocardial infarction or myocardial injury
C
Comparator
Type 1 myocardial infarction
O
Outcome
All-cause death at 5 yearshard clinical
Main Result
Absolute Event Rate: 62.5% vs 36.7%
Patients with type 2 myocardial infarction or myocardial injury experience higher long-term all-cause mortality than those with type 1 MI, primarily due to noncardiovascular causes, though crude MACE rates are similar.
Cite This Study
Chapman et al. (2017) conducted a cohort in Type 2 myocardial infarction and myocardial injury (n=2,122). Type 2 myocardial infarction or myocardial injury vs. Type 1 myocardial infarction was evaluated on all-cause death. Type 2 myocardial infarction and myocardial injury were associated with higher 5-year all-cause death rates (62.5% and 72.4%, respectively) compared with type 1 myocardial infarction (36.7%).