Key result
Acute myocardial injury was associated with a higher adjusted risk of all-cause mortality compared with chronic myocardial injury (HR 1.21; 95% CI 1.08 to 1.36) over 3.9 years.
Why the study?
Data were limited regarding the long-term prognosis of patients with acute versus chronic myocardial injury.
Do long-term outcomes differ between acute myocardial injury, type 1 MI, type 2 MI, and chronic myocardial injury in patients presenting to the emergency department with elevated hs-cTnT?
Population
3853 emergency department patients with hs-cTnT >14 ng/L
Comparison
Acute myocardial injury, T1MI, or T2MI vs chronic myocardial injury
Design
Observational cohort study
Follow-up
3.9 (±2) years
Authors
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Similar long-term mortality risks seen in acute versus chronic myocardial injury; leaves open whether management should differ pending prospective data.
Cohort (n=3,853)
Do long-term outcomes differ between acute myocardial injury, type 1 MI, type 2 MI, and chronic myocardial injury in patients presenting to the emergency department with elevated hs-cTnT?
Hazard Ratio: 1.21 (95% CI 1.08–1.36)
Absolute Event Rate: 48% vs 49%
Both acute and chronic myocardial injury are associated with very high long-term mortality, with acute injury and T2MI carrying slightly higher adjusted mortality risks than chronic injury.
Kadesjö et al. (2019) conducted a cohort in Myocardial injury (n=3,853). Acute myocardial injury vs. Chronic myocardial injury was evaluated on all-cause mortality (HR 1.21, 95% CI 1.08 to 1.36). Acute myocardial injury was associated with a higher adjusted risk of all-cause mortality compared with chronic myocardial injury (HR 1.21; 95% CI 1.08 to 1.36) over 3.9 years.
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