Key result
Microalbuminuria was significantly associated with hypertension (OR 3.5; 95% CI 1.2-9.7) among type 2 diabetic patients and healthy individuals.
Why the study?
Microalbuminuria marks glomerular injury and cardiovascular risk, and hypertension frequently coexists with diabetes mellitus, prompting investigation into microalbuminuria prevalence and its relationship with hypertension in these populations.
Cross-Sectional (n=107)
Answers are grounded in this paper and cite their sources.
Microalbuminuria is highly prevalent in both diabetic and general populations and is significantly associated with hypertension, highlighting the need for early screening.
Background: Microalbuminuria is a clinical marker of glomerular injury and identified as a risk of progressive renal damage, cardiovascular disease and morbidity. Hypertension (HTN) is a worldwide public health problem andcommonly coexists with Diabetes Mellitus (DM). Objective: The aim of the study was todetermine the prevalence of microalbuminuriain type 2diabetic patients and general people and the relationship between microalbuminuria withHTN and other clinical parametersin these twogroups of people. Methodology: A cross-sectional study was carried out using a pretested structured questionnaire amongrandomly selected107 participants aged from 35-70 years. Out of 107 participants 64 persons were type 2 diabetic patients and 43 were healthy individuals. Biochemical analysis of blood and urine samples was performed. Result: The prevalence of microalbuminuria was 17.2% in diabetic patients and 25.6% ingeneral people whereas the prevalence of HTN was 48.4% among diabetic patients and 51.6% in normal healthy persons. Regardless of the group considered, when microalbuminuria was analyzed according to the different clinical parameters, microalbuminuricpatients had significantly highersystolic (p=0.03) diastolic (p=0.02) blood pressure, urine creatinine (p=0.000), serum creatinine (p=0.012), urine albumin (p=0.019) and GFR (p=0.000). Microalbuminuria was found to be associated with HTN (odds ratio [OR] 3.5, 95% confidence interval [CI] 1.2-9.7). Conclusion: The study concluded thatmicroalbuminuria prevalence is high among general people and HTN has a significant relationship with microalbuminuria. These findings suggest early screening of microalbuminuria and the proper management of other clinical parameters to halt and prevent end stage renal disease and cardiovascular risk in future.
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Monir et al. (2019) conducted a cross-sectional in Type 2 Diabetes Mellitus and healthy individuals (n=107). Microalbuminuria vs. No microalbuminuria was evaluated on Hypertension (OR 3.5, 95% CI 1.2-9.7). Microalbuminuria was significantly associated with hypertension (OR 3.5; 95% CI 1.2-9.7) among type 2 diabetic patients and healthy individuals.
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