Why the study?
Does depression or anxiety increase the risk of mortality and MACE in patients with and without coronary artery disease?
Population
2,390 patients referred to the Montreal Heart Institute, with and without coronary artery disease (CAD)
Comparison
Presence of depression or anxiety vs Absence of depression or anxiety
Design
Cohort
Follow-up
8.8 years
Authors
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Depression may warrant attention for mortality risk in non-CAD patients; leaves open whether screening or treatment improves outcomes.
Does depression or anxiety increase the risk of mortality and MACE in patients with and without coronary artery disease?
Depression, but not anxiety, is an independent risk factor for all-cause mortality, particularly in patients without established coronary artery disease.
Pelletier et al. (2015) studied this question.
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