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February 1, 1992Archives of Internal Medicine

Identification of Severe Coronary Artery Disease Using Simple Clinical Parameters

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Key result

A five-point clinical risk scale successfully estimated the likelihood of severe coronary disease, identifying three-vessel or left-main disease in 48% of high-risk and 9% of low-risk patients.

Why the study?

Can simple clinical and resting electrocardiographic variables predict the probability of three-vessel or left-main coronary artery disease in patients with symptomatic CAD?

Population

680 patients with symptomatic coronary artery disease who underwent exercise equilibrium radionuclide…

Design

Cross-sectional

Authors

BHBradley HubbardTrinity Health

Discussion

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Implication

May aid bedside risk stratification in symptomatic CAD; leaves open prospective validation before practice change.

Study Design

Type

Observational (n=680)

Structured PICO

Can simple clinical and resting electrocardiographic variables predict the probability of three-vessel or left-main coronary artery disease in patients with symptomatic CAD?

P
Population
680 patients with symptomatic coronary artery disease who underwent exercise equilibrium radionuclide angiography and coronary angiography within 6 months.
E
Exposure
Five-point cardiac risk scale based on clinical and resting electrocardiographic variables (age, typical angina, diabetes, gender, and history/ECG evidence of prior myocardial infarction)
O
Outcome
Presence of three-vessel or left-main coronary artery diseasesurrogate

A simple five-point clinical risk scale using age, typical angina, diabetes, gender, and prior MI can effectively estimate the likelihood of severe (three-vessel or left-main) coronary artery disease.

Cite This Study

Bradley Hubbard (1992) conducted an observational in Symptomatic coronary artery disease (n=680). Five-point clinical risk scale (age, typical angina, diabetes, gender, prior MI) was evaluated on Probability of three-vessel or left-main coronary artery disease. A five-point clinical risk scale successfully estimated the likelihood of severe coronary disease, identifying three-vessel or left-main disease in 48% of high-risk and 9% of low-risk patients.

synapsesocial.com/papers/6a225abd3dc1edca6bb60428https://doi.org/10.1001/archinte.1992.00400140061014
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical Indicators of Left Main Coronary Artery Disease in Unstable Angina1979 · 56 citations
  2. 2The role of the exercise test in the evaluation of patients for ischemic heart disease.1978 · 499 citations
  3. 3Bayesian Analysis of Electrocardiographic Exercise Stress Testing1977 · 283 citations
  4. 4Survival of medically treated patients in the coronary artery surgery study (CASS) registry.1982 · 744 citations
  5. 5Use of treadmill score to quantify ischemic response and predict extent of coronary disease.1979 · 114 citations