Recovery-phase patterns of ST segment depression in the heart rate domain. Identification of coronary artery disease by the rate-recovery loop.
Why the study?
Does the rate-recovery loop improve the identification of coronary artery disease compared to standard ST segment depression criteria during treadmill exercise?
Population
241 subjects including 100 clinically normal subjects, 124 patients with catheterization-proven coronary…
Comparison
Rate-recovery loop vs Standard end-exercise ST segment depression…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May enhance CAD detection sensitivity on treadmill testing; leaves open prospective validation before practice change.
Structured PICO
Does the rate-recovery loop improve the identification of coronary artery disease compared to standard ST segment depression criteria during treadmill exercise?
P
Population
241 subjects including 100 clinically normal subjects, 124 patients with catheterization-proven coronary artery disease, and 17 patients with no significant coronary disease at catheterization.
I
Intervention
Rate-recovery loop (continuous plots of ST segment depression and heart rate throughout treadmill exercise and recovery)
C
Comparator
Standard end-exercise ST segment depression criteria
O
Outcome
Sensitivity and specificity for identifying coronary artery diseasesurrogate
The rate-recovery loop during treadmill exercise significantly improves the sensitivity of detecting coronary artery disease compared to standard ST segment depression criteria without compromising specificity.
Cite This Study
Okin et al. (1989) studied this question.