What question did this study set out to answer?

To evaluate the relationship between exercise-induced S-T segment depression and coronary artery disease.

November 1, 1972CirculationOpen Access

Maximal Treadmill Exercise Electrocardiography

View Full Paper

Ask AI

Bookmark

Why the study?

Does maximal treadmill exercise electrocardiography accurately predict the presence of coronary artery disease and abnormal hemodynamics in patients with chest pain?

Population

100 patients evaluated for chest pain

Comparison

Maximal treadmill exercise electrocardiography vs Coronary arteriography, left ventricular…

Design

Cross-sectional

Authors

CMCarroll M. MartinMadigan Army Medical Center DMDavid R. McConahaySaint Luke's Hospital

Discussion

Member takes

Implication

≥1 mm ST depression specifically flags CAD and links to elevated filling pressures; supports noninvasive assessment but leaves open prospective validation.

Key Points

To evaluate the relationship between exercise-induced S-T segment depression and coronary artery disease.
Electrocardiograms recorded during maximal treadmill exercise in 100 patients.
Correlations made with coronary arteriograms and left ventricular cineangiograms.
Assessment of hemodynamics at rest and during exercise.
1.0 mm or greater S-T depression predicted CAD presence with 89% specificity and 62% sensitivity.
S-T depression of ≧0.75 mm and ≧0.5 mm improved sensitivities to 68% and 84%, respectively.
Significant correlation between exercise-induced S-T depression and pulmonary artery wedge pressure (P < 0.005).

Structured PICO

Does maximal treadmill exercise electrocardiography accurately predict the presence of coronary artery disease and abnormal hemodynamics in patients with chest pain?

Population

100 patients evaluated for chest pain

Intervention

Maximal treadmill exercise electrocardiography

Comparator

Coronary arteriography, left ventricular cineangiography, and invasive cardiac hemodynamics (reference standards)

Outcome

Diagnostic accuracy (sensitivity and specificity) of exercise-induced S-T segment depression for predicting the presence and extent of coronary artery disease (CAD)surrogate

Maximal treadmill exercise testing using a ≧1.0 mm S-T depression criterion provides a specific noninvasive method for predicting significant coronary artery disease and is associated with abnormal left ventricular filling pressures during exercise.

Cite This Study

Martin et al. (1972) studied this question.

synapsesocial.com/papers/6a225abe3dc1edca6bb6042e https://doi.org/10.1161/01.cir.46.5.956

View Full Paper

Ask AI

Bookmark

Implication

≥1 mm ST depression specifically flags CAD and links to elevated filling pressures; supports noninvasive assessment but leaves open prospective validation.

Maximal Treadmill Exercise Electrocardiography

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Maximal Treadmill Exercise Electrocardiography

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider