Key result
Anti-inflammatory medication over reliever-only treatment maximizes outcomes and maintains long-term remission in mild asthma.
Why the study?
Mild asthma is difficult to define due to its heterogeneity and wide spectrum of impact and outcomes, including risk of severe exacerbations.
Guidelines support initiating anti-inflammatory medication and avoiding reliever-only treatment for mild asthma to maximize patient outcomes and achieve long-term remission.
Supports avoiding reliever-only regimens in mild asthma; leaves open randomized confirmation of remission durability.
Mild and moderate asthma cover a wide range of asthma presentations, phenotypes and symptom burden, and account for the majority of people with asthma worldwide. Mild asthma has been difficult to define because of its heterogeneity and wide spectrum of impact and outcomes, including being associated with severe exacerbations. Assessment of mild-moderate asthma is best made by combining asthma symptom control and exacerbation risk as the principle means by which to determine treatment needs. Incontrovertible evidence and guidelines support treatment initiation with anti-inflammatory medication, completely avoiding reliever-only treatment of mild asthma. Shared decision making with patients and a treatable traits approach will ensure that a holistic approach is taken to maximize patient outcomes. Most importantly, mild asthma should be regarded as a reversible, potentially curable condition, remaining in long-term remission through minimizing triggers and optimizing care.
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Christine Jenkins (2023) conducted a review in Mild and moderate asthma. Anti-inflammatory medication vs. Reliever-only treatment was evaluated. Anti-inflammatory medication, completely avoiding reliever-only treatment, is recommended for mild asthma to maximize patient outcomes and maintain long-term remission.
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