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June 5, 2026Case Reports in RheumatologyOpen Access

Successful Treatment of Anti‐Jo‐1 Positive Inflammatory Myopathy With Tofacitinib

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Authors

JTJanis TimsansAHAnna‐Mari HokkanenJRJoonas Rautavaara

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Overview

Case report shows improved symptoms in anti-Jo-1 positive myopathy following tofacitinib treatment, suggesting new options.

Key Points

  • This case report aims to evaluate the effectiveness of tofacitinib in treating refractory inflammatory myopathy associated with anti-Jo-1 antibodies.
  • Patient: middle-aged woman with severe myositis symptoms
  • Treatment: initiated tofacitinib after multiple failed immunosuppressant therapies
  • Outcome measures: clinical improvement and creatinine kinase normalization
  • Significant clinical improvement observed after starting tofacitinib
  • Creatinine kinase levels normalized
  • Glucocorticoids could be safely discontinued

Cite This Study

Timsans et al. (2026) studied this question.

synapsesocial.com/papers/6a226851763171746d546f19https://doi.org/10.1155/crrh/6478835
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Also Consider

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  1. 1Successful treatment of tofacitinib-refractory scleritis associated with multiple systemic inflammatory diseases using upadacitinib2025
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