Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
June 5, 2026Journal of Minimal Access SurgeryOpen Access

Laparoscopic versus open pancreaticoduodenectomy in patients with periampullary carcinoma: A randomised clinical trial

View Full Paper
Ask AI
Bookmark
Share

Authors

VCVivek ChauhanASAditya SharmaHNHirdaya H. Nag

Discussion

Loading...

Member takes

Overview

Randomized trial compares intraoperative blood loss in laparoscopic and open pancreaticoduodenectomy, indicating safety and feasibility in patients.

Key Points

  • This trial aims to compare laparoscopic and open pancreaticoduodenectomy regarding blood loss and oncological outcomes.
  • Single-centre, prospective, single-blind randomized controlled trial conducted from January 2018 to December 2021.
  • Resectable periampullary carcinoma patients were randomized to laparoscopic PD (LPD) or open PD (OPD).
  • Primary endpoint was intra-operative blood loss; secondary endpoints included hospital stay, complications, overall survival, and recurrence-free survival.
  • Mean blood loss was significantly lower in LPD (P=0.046).
  • Three-year overall survival and two-year recurrence-free survival rates were comparable between LPD and OPD groups.
  • One patient in the LPD group had an R1 resection, while the rest achieved R0.

Cite This Study

Chauhan et al. (2026) studied this question.

synapsesocial.com/papers/6a2269a2763171746d548471https://doi.org/10.4103/jmas.jmas_581_25
View Full Paper
Ask AI
Bookmark
Share