Key result
Following PCI, obese class III patients with high-risk coronary anatomy and no diabetes had significantly higher 5-year mortality (HR 1.78; 95% CI 1.11-2.85) compared to normal BMI.
Why the study?
Does BMI category affect short- and long-term all-cause mortality in patients undergoing CABG or PCI?
Cohort (n=37,818)
Does BMI category affect short- and long-term all-cause mortality in patients undergoing CABG or PCI?
The obesity paradox is observed in overweight patients after coronary revascularization, but class III obesity is associated with higher long-term mortality after PCI in high-risk patients without diabetes.
Answers are grounded in this paper and cite their sources.
Class III obesity may signal higher long-term post-PCI mortality in high-risk non-diabetics; leaves open whether this extends to other populations or interventions.
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Terada et al. (2017) conducted a cohort in Coronary artery disease requiring CABG or PCI (n=37,818). Overweight and obesity (BMI ≥25.0) vs. Normal BMI (18.5-24.9) was evaluated on All-cause mortality at 5 years (obese class III without diabetes following PCI) (HR 1.78, 95% CI 1.11-2.85). Following PCI, obese class III patients with high-risk coronary anatomy and no diabetes had significantly higher 5-year mortality (HR 1.78; 95% CI 1.11-2.85) compared to normal BMI.
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