What question did this study set out to answer?

Q: What question did this study set out to answer?

To determine the impact of body mass index on long-term all-cause mortality in patients undergoing first-time elective percutaneous coronary intervention.

August 17, 2009ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)Open Access

Obesity paradox in a cohort of 4880 consecutive patients undergoing percutaneous coronary intervention

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Why the study?

Does increased BMI (≥27.5 and <30) reduce long-term all-cause mortality in patients undergoing first-time elective PCI compared to normal weight?

Population

4,880 patients undergoing first-time elective percutaneous coronary intervention in Scotland between April…

Comparison

BMI ≥27.5 and <30 vs Normal weight individuals

Design

Cohort

Follow-up

5 years

Authors

CHClaire E. HastieUniversity of Glasgow SPSandosh PadmanabhanPreventive Cardiology RSR. SlackWestern Health

Discussion

Member takes

Implication

Should not yet alter weight counseling after elective PCI; leaves open whether the obesity paradox reflects confounding or true benefit.

Key Points

To determine the impact of body mass index on long-term all-cause mortality in patients undergoing first-time elective percutaneous coronary intervention.
Analyzed registry data from the Scottish Coronary Revascularisation Register on N=4,880 consecutive patients undergoing elective PCI between April 1997 and March 2006, excluding those with prior revascularization.
Evaluated 5-year all-cause mortality across body mass index categories, adjusting for age, hypertension, diabetes, and left ventricular function.
A total of 219 deaths occurred within 5 years across 4,880 elective procedures.
Patients with a BMI ≥27.5 and <30 kg/m² had significantly lower 5-year mortality compared to normal-weight individuals (unadjusted HR 0.59, 95% CI 0.39–0.90, P=0.014; adjusted HR 0.59, 95% CI 0.39–0.90, P=0.015).
The survival advantage for higher BMI remained consistent after restricting analysis to outcomes occurring beyond 30 days of follow-up.

Structured PICO

Does increased BMI (≥27.5 and <30) reduce long-term all-cause mortality in patients undergoing first-time elective PCI compared to normal weight?

Population

4,880 patients undergoing first-time elective percutaneous coronary intervention (PCI) in Scotland between April 1997 and March 2006. Excluded: patients who had previously undergone revascularization.

Intervention

BMI ≥27.5 and <30

Comparator

Normal weight individuals

Outcome

Long-term all-cause mortality within 5 yearshard clinical

In patients undergoing first-time elective PCI, a BMI between 27.5 and 30 is associated with improved 5-year survival compared to normal weight, supporting the existence of an obesity paradox.

Cite This Study

Hastie et al. (2009) studied this question.

synapsesocial.com/papers/6a1004185725bbd5cc6063a3 https://doi.org/10.1093/eurheartj/ehp317

Topics

Coronary artery disease Hypertension management

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Obesity paradox in a cohort of 4880 consecutive patients undergoing percutaneous coronary intervention

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Obesity paradox in a cohort of 4880 consecutive patients undergoing percutaneous coronary intervention

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider