Echocardiographic Correlates of Cardiac Fibrosis in Patients With Myocardial Infarction and Preserved Left Ventricular Ejection Fraction

Aim. To identify the possibilities of echocardiography in the evaluation of myocardial fibrosis inт patients with ST segment elevation myocardial infarction (STEMI).Materials and Methods. We recruited 70 consecutive patients who have undergone percutaneous coronary intervention due to STEMI. Echocardiography was performed at the time of admission, on 8th-10th day post-admission and one year after STEMI to evaluate left ventricular ejection fraction. Assessment of cardiac fibrosis was carried out at the latter time point using magnetic resonance imaging.Results. All patients had the signs of cardiac fibrosis, yet they were more pronounced in those with decreased LVEF (40-49%). A positive correlation was observed between the extent of cardiac fibrosis and LV dimensions at the admission (p = 0.01) while the correlation of cardiac fibrosis with LVEF was negative (r = -0.30, p=0.01) at all the time points. Cardiac fibrosis was associated both with systolic and diastolic dysfunction.Conclusion. Echocardiographic evaluation of LVEF can be useful in making diagnosis and evaluating severity of cardiac fibrosis in patients with STEMI.