Why the study?
Do plasma concentrations of thromboxane B2 differ between patients with Prinzmetal's variant angina and classical angina pectoris?
Population
22 patients, comprising 14 with classical angina pectoris and 8 with Prinzmetal's variant angina.
Comparison
Measurement of plasma thromboxane B2 levels… vs Comparison between variant angina and classical…
Design
Cohort
Authors
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Thromboxane B2 elevation may mark variant angina activity; this Level 3 cohort finding leaves open any therapeutic role pending trials.
Do plasma concentrations of thromboxane B2 differ between patients with Prinzmetal's variant angina and classical angina pectoris?
Thromboxane B2 levels are higher in variant angina compared to classical angina and increase following ischemic episodes in both conditions, suggesting a potential role in coronary spasm and ischemia.
Lewy et al. (1979) studied this question.
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