Key result
Three patients with oral cancer developed pulmonary embolism during chemotherapy, chemoradiotherapy, or the perioperative period, highlighting the need for VTE risk assessment before treatment.
Why the study?
Patients with oral cancer undergoing reconstructive surgery or chemotherapy are at risk for venous thromboembolism, including pulmonary embolism and deep vein thrombosis.
Case Report (n=3)
Highlights the risk of venous thromboembolism, including pulmonary embolism, in patients undergoing treatment for oral cancer, emphasizing the need for pre-treatment risk assessment.
Alerts to VTE risk in oral cancer treatment; leaves open whether routine prophylaxis improves outcomes.
Background Venous thromboembolism (VTE), including pulmonary embolism (PE) and deep vein thrombosis (DVT), is known to occur frequently during the perioperative period. Particularly, patients with oral cancer (OC) who undergo reconstructive surgery are at risk of VTE in oral and maxillofacial surgery. Additionally, chemotherapy is an independent risk factor for thromboembolic events in patients with cancer. Case Presentation In this report, we present three cases that developed PE during OC treatment. One case developed PE during chemotherapy, and the other two cases developed PE and DVT during chemoradiotherapy and the perioperative period. Conclusion Before treatment, the risk assessment should be undertaken in patients with OC who undergo surgery or chemotherapy.
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Uchida et al. (2022) conducted a case report in Oral cancer (n=3). Oral cancer treatment (chemotherapy, chemoradiotherapy, surgery) was evaluated on Development of pulmonary embolism (PE) and deep vein thrombosis (DVT). Three patients with oral cancer developed pulmonary embolism during chemotherapy, chemoradiotherapy, or the perioperative period, highlighting the need for VTE risk assessment before treatment.
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