Key result
Incubation of poliovirus in anaerobically digested sludge decreased its infectivity at a rate ranging from >1 log/day at 28 C to ~1 log/5 days at 4 C, likely due to RNA inactivation.
Population
Poliovirus in anaerobically digested sludge
Comparison
Incubation at temperatures between 28 and 4 C vs Raw sludge
Design
Preclinical
Authors
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May inform sludge treatment temperatures for poliovirus control; leaves open applicability to other viruses and real-world conditions.
Anaerobically digested sludge inactivates poliovirus through a mechanism involving viral protein cleavage and RNA nicking, an effect not seen in raw sludge.
Ward et al. (1976) studied Poliovirus inactivation. Anaerobically digested sludge vs. Raw sludge was evaluated on Virus infectivity and inactivation rate. Incubation of poliovirus in anaerobically digested sludge decreased its infectivity at a rate ranging from >1 log/day at 28 C to ~1 log/5 days at 4 C, likely due to RNA inactivation.
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