Key result
Inter-reader differences in carotid intima-media thickness measurements ranged from 0.57 to 0.78 mm (P<0.009) and were significantly associated with media-adventitia interface location (P<0.0001).
Why the study?
How do inter-reader differences in tracing wall interfaces affect common carotid artery intima-media thickness measurements and vascular age estimates?
Observational (n=26)
Single-blind
How do inter-reader differences in tracing wall interfaces affect common carotid artery intima-media thickness measurements and vascular age estimates?
p-value: p=<0.009
Significant inter-reader variability in carotid intima-media thickness measurements, primarily driven by media-adventitia interface tracing, can cause substantial errors in vascular age estimates.
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CIMT variability may limit clinical reliability for vascular age; leaves open standardization of media-adventitia tracing in research.
Polak et al. (2011) conducted an observational in Atherosclerosis (n=26). Tracing of carotid wall interfaces vs. Different readers was evaluated on Mean intima-media thickness measurements (p=<0.009). Inter-reader differences in carotid intima-media thickness measurements ranged from 0.57 to 0.78 mm (P<0.009) and were significantly associated with media-adventitia interface location (P<0.0001).
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