Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 23, 2010ImmunologyOpen Access

PD-1 negatively regulates interleukin-12 expression by limiting STAT-1 phosphorylation in monocytes/macrophages duringchronic hepatitis C virus infection

View Full Paper
Ask AI
Bookmark
Share

Authors

JCJun ChengRenji HospitalLNLei NiDongzhimen Hospital Affiliated to Beijing University of Chinese MedicineYZYing ZhangZunyi Medical University

Discussion

Loading...

Member takes

Overview

Key Points

Key points are not available for this paper at this time.

Cite This Study

Cheng et al. (2010) studied this question.

synapsesocial.com/papers/6a229a880ae3bb3db2cd3c95https://doi.org/10.1111/j.1365-2567.2010.03382.x
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production2007 · 110 citations
  2. 2IL-12p40 and IL-18 Play Pivotal Roles in Orchestrating the Cell-Mediated Immune Response to a Poxvirus Infection2009 · 51 citations
  3. 3PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine2001 · 852 citations
  4. 4B7‐H1 up‐regulation impairs myeloid DC and correlates with disease progression in chronic HIV‐1 infection2008 · 54 citations
  5. 5Impaired Effector Function of Hepatitis C Virus-Specific CD8+ T Cells in Chronic Hepatitis C Virus Infection2002 · 636 citations