Key result
The presence of non-obstructive CT low-dense plaques significantly increased the risk of acute coronary syndrome compared to patients without such plaques (OR 2.53).
Why the study?
Does the presence of non-obstructive CT low-dense plaques (CTLDP) predict acute coronary syndrome and cardiac death in patients with non-obstructive coronary artery disease?
Population
810 patients with non-obstructive coronary artery disease who underwent multislice computed tomography, mean…
Comparison
Presence of non-obstructive CT low-dense plaques… vs Absence of CTLDP
Design
Cohort
Follow-up
mean 1,062+/-544 days
Authors
Loading...
May identify higher ACS risk on CT in non-obstructive CAD; hypothesis-generating for plaque characterization in future risk models.
Cohort (n=810)
Single-blind
No
Does the presence of non-obstructive CT low-dense plaques (CTLDP) predict acute coronary syndrome and cardiac death in patients with non-obstructive coronary artery disease?
Odds Ratio: 2.53 (95% CI 1.08–5.92)
Absolute Event Rate: 5.29% vs 1.93%
p-value: p=<0.05
Non-obstructive CT low-dense plaques detected by MSCT provide independent prognostic information for predicting future acute coronary syndromes.
Matsumoto et al. (2007) conducted a cohort in Non-obstructive coronary artery disease (n=810). Presence of non-obstructive CT low-dense plaques (CTLDP) vs. Absence of CTLDP was evaluated on Acute coronary syndrome (ACS) (OR 2.53, 95% CI 1.08-5.92, p=<0.05). The presence of non-obstructive CT low-dense plaques significantly increased the risk of acute coronary syndrome compared to patients without such plaques (OR 2.53).
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: