Key result
Myocardial inflammation is tightly regulated by mechanisms including strong central and peripheral T cell tolerance and anti-inflammatory feedback involving cytokines such as interferon-gamma.
This review emphasizes the delicate balance of myocardial inflammatory responses and the unique regulatory mechanisms that protect the heart from maladaptive immunity.
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Should not yet change management of cardiac inflammation; leaves open targeted modulation of T cell tolerance mechanisms.
Taqueti et al. (2005) conducted a review in Myocardial inflammation. Myocardial inflammation is tightly regulated by mechanisms including strong central and peripheral T cell tolerance and anti-inflammatory feedback involving cytokines such as interferon-gamma.
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