What question did this study set out to answer?

This research aimed to investigate the hormonal patterns and responses to tests in women with polycystic ovarian syndrome compared to controls.

Pituitary-Ovarian Relationships in Polycystic Ovary Syndrome

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Randomized trial measures hormonal responses in polycystic ovary syndrome, indicating possible estrogen influence.

This research aimed to investigate the hormonal patterns and responses to tests in women with polycystic ovarian syndrome compared to controls.
Measured gonadotropins and ovarian steroids in 12 women with polycystic ovarian syndrome and 6 normal women during the early follicular phase.
Assessed urinary total estrogen and pregnanediol over 12 weeks.
Evaluated feedback responses to an estrogen provocation test and LRF stimulation.
75% of cycles in PCO patients were anovulatory compared to 100% ovulatory in controls.
Basal LH was significantly higher, and FSH was significantly lower in anovulatory PCO versus controls (P < 0.05).
LH peak occurred 24 hours earlier in anovulatory PCO after estrogen provocation than in controls.

Baird et al. (1977) studied this question.

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