The translational control of vertebrate mRNAs with a 5'-terminal pyrimidine tract is conserved across vertebrate classes and requires both the 5' TOP and immediately downstream sequences.
No takes yet. Share an insight, caveat, or question.
No immediate clinical implications; extends 5' TOP regulation to non-ribosomal mRNAs in vertebrate models.
Avni et al. (1994) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: