Key result
Exposure to high K solutions (20, 40, or 60 mM) reduced the resting potential but did not change the cell-to-cell diffusion of Lucifer Yellow CH in dog atrial trabeculae.
Population
Dog atrial trabeculae
Comparison
High K solution (20, 40, or 60 mM) vs Normal heart muscle (control)
Design
Preclinical
Authors
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Supports membrane potential-independent gap junction permeability in canine atrium; leaves open relevance to human disease or in vivo conditions.
Junctional permeability in heart muscle is not influenced by the non-junctional membrane potential.
DEMELLO et al. (1987) studied Normal heart muscle. High K solution vs. Control (normal heart muscle) was evaluated on Cell-to-cell diffusion of Lucifer Yellow CH. Exposure to high K solutions (20, 40, or 60 mM) reduced the resting potential but did not change the cell-to-cell diffusion of Lucifer Yellow CH in dog atrial trabeculae.
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