Key result
Preoperative P-wave dispersion was significantly associated with the risk of postoperative atrial fibrillation after CABG (HR 1.05; 95% CI 1.001-1.103; p=0.048), whereas LAVI was not.
Why the study?
Preoperative left atrial remodeling can predispose to postoperative atrial fibrillation (POAF), but the predictive value of left atrial volume index (LAVI) and P-wave dispersion needed assessment in patients undergoing CABG.
Do preoperative P-wave dispersion and LAVI predict postoperative atrial fibrillation in patients undergoing CABG?
Cohort (n=42)
Do preoperative P-wave dispersion and LAVI predict postoperative atrial fibrillation in patients undergoing CABG?
Hazard Ratio: 1.05 (95% CI 1.001–1.103)
p-value: p=0.048
Preoperative P-wave dispersion, but not left atrial volume index, is a significant predictor of postoperative atrial fibrillation in patients undergoing CABG.
P-wave dispersion may aid POAF risk stratification after CABG; leaves open incremental value beyond clinical factors and requires prospective validation.
Background: Preoperative left atrial remodeling as Postoperative atrial fibrillation (POAF) predisposing factors could be measured by left atrial volume index (LAVI) and P-wave dispersion. Aim: This study aimed to assess P-wave dispersion and LAVI as preoperative predictors of POAF among patients who underwent Coronary Artery Bypass Graft (CABG). Methods: An analytical retrospective cohort study was performed on patients who underwent CABG. The P-wave dispersion and POAF were evaluated based on documented ECG results. LAVI size was collected from echocardiographic reports. Hazard ratios of P-wave dispersion and LAVI for POAF were analyzed using Cox proportional hazard model. Result: A total of 42 subjects (57±1 years) were included in this study. POAF occurred in 28.6% of patients at a median of 2 days after CABG. P-wave dispersion was significantly longer in patients in whom AF was developed (53.03±3.82ms vs. 44.01±1.98ms, p:0.028), while LAVI difference was not significant. The Cox proportional hazard model showed a significant association between P-wave dispersion and risk of POAF (HR 1.05, CI95%, 1.001-1.103;p=0.048). There was no association between LAVI and risk of POAF (HR1.003, CI 95%, 0.965-1.044;p=0.864). Conclusion: P-wave dispersion is a predictor of POAF in patients who underwent CABG. Risk stratification using P-wave dispersion enables clinicians to identify high-risk patients before CABG surgery.
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Achmad et al. (2022) conducted a cohort in Coronary Artery Bypass Graft (CABG) (n=42). P-wave dispersion was evaluated on Postoperative atrial fibrillation (POAF) (HR 1.05, 95% CI 1.001-1.103, p=0.048). Preoperative P-wave dispersion was significantly associated with the risk of postoperative atrial fibrillation after CABG (HR 1.05; 95% CI 1.001-1.103; p=0.048), whereas LAVI was not.
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