Key result
Pulmonary capillary wedge pressure showed only a modest correlation with left ventricular end-diastolic volume (r = 0.302; p < 0.01) when omitting PEEP, making it a poor predictor of preload.
Why the study?
Does pulmonary capillary wedge pressure predict left ventricular preload in critically ill patients with sepsis and cardiac disease?
Population
Acutely ill patients with sepsis and cardiac disease
Comparison
Measurement of pulmonary capillary wedge pressure vs Measurement of left ventricular end-diastolic…
Design
Cross-sectional
Authors
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PCWP should not guide preload assessment in critically ill patients; leaves open whether LV compliance explains discordance in prospective studies.
Observational
Does pulmonary capillary wedge pressure predict left ventricular preload in critically ill patients with sepsis and cardiac disease?
Effect estimate: r = 0.302
p-value: p=<0.01
Pulmonary capillary wedge pressure is a poor predictor of left ventricular preload in critically ill patients, likely due to abnormalities in left ventricular compliance.
Calvin et al. (1981) conducted an observational in Sepsis and cardiac disease in critically ill patients. Pulmonary capillary wedge pressure (PWP) was evaluated on Relationship between left ventricular end-diastolic volume (LVEDV) and PWP (r = 0.302, p=<0.01). Pulmonary capillary wedge pressure showed only a modest correlation with left ventricular end-diastolic volume (r = 0.302; p < 0.01) when omitting PEEP, making it a poor predictor of preload.
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