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June 28, 2014Nutrition JournalOpen Access

A single consumption of curry improved postprandial endothelial function in healthy male subjects: a randomized, controlled crossover trial

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Key result

A single consumption of a curry meal significantly improved postprandial flow-mediated vasodilation to 6.6% compared to 5.1% after a spice-free control meal in healthy men.

Why the study?

Does a single consumption of a curry meal improve postprandial endothelial function in healthy male subjects?

Population

14 healthy male subjects, mean age 45 ± 9 years, BMI 23.7 ± 2.7 kg/m2

Comparison

Single serving of curry meal vs Spice-free control meal

Design

RCT, Randomized crossover design

Follow-up

1 hour

Authors

HNHideki NakayamaNTNobuaki TsugeHSHiroshi Sawada

Discussion

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Overview

May support curry for acute endothelial benefits in healthy men; extends RCT evidence on dietary spices.

Study Design

Type

RCT (n=14)

Blinding

Single-blind

Randomization

Randomized

Multicenter

No

Structured PICO

Does a single consumption of a curry meal improve postprandial endothelial function in healthy male subjects?

P
Population
14 healthy men aged 33 to 64 years without cardiovascular risk factors, evaluated for postprandial endothelial function 1 hour after a single meal.
I
Intervention
Single serving of curry meal (180 g of curry and 200 g of cooked rice; approximately 500 kcal in total)
C
Comparator
Spice-free control meal (180 g of control and 200 g of cooked rice; approximately 500 kcal in total)
O
Outcome
Postprandial flow-mediated vasodilation (FMD) response 1 hour after consumptionsurrogate

Main Result

Absolute Event Rate: 6.6% vs 5.1%

p-value: p=0.002

A single consumption of a curry meal significantly improved postprandial endothelial function compared to a spice-free control meal in healthy men.

Limitations

  • Small sample size (n = 14)
  • Curry meals were readily distinguishable from the control meals by the subjects due to unique flavor and color

Cite This Study

Nakayama et al. (2014) conducted an RCT in Healthy (n=14). Curry meal vs. Spice-free control meal was evaluated on Postprandial flow-mediated vasodilation (FMD) at 1 hour (p=0.002). A single consumption of a curry meal significantly improved postprandial flow-mediated vasodilation to 6.6% compared to 5.1% after a spice-free control meal in healthy men.

synapsesocial.com/papers/6a22aa5d519b89fa360df201https://doi.org/10.1186/1475-2891-13-67
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Also Consider

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