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The aim is to review advancements in asymmetric hydroalkoxylation and its mechanism related to other hydrofunctionalization methods.

December 3, 2021Chemical ReviewsOpen Access

Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds

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The aim is to review advancements in asymmetric hydroalkoxylation and its mechanism related to other hydrofunctionalization methods.
Survey of recent innovations in asymmetric hydroalkoxylation methods.
Analysis of selectivity parameters in catalytic processes.
Comparison with related methods like hydroacyloxylation and hydration.
Emergence of effective catalytic enantioselective techniques for alcohol additions to C-C multiple bonds.
Notable progress in employing chiral Brønsted acids and photocatalytic methods.
Identification of ongoing challenges and the need for interdisciplinary collaboration in the field.

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Review highlights advances and challenges in asymmetric hydroalkoxylation of C-C multiple bonds, suggesting innovation pathways.

Kennemur et al. (2021) studied this question.

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