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提出了一种通过NaCl解离和羟基磷灰石色谱法纯化组蛋白组H2A+H2B和H3+H4的方法。该程序简单,涉及温和的溶剂,并提供高纯度的毫克级组蛋白。通过此方法制备的组蛋白对在与DNA结合和重构时可以再生染色质样特性。
Simon等(Mon,)研究了这个问题。
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