Why the study?
Does aPTT correlate with plasma dabigatran concentration in Japanese patients with non-valvular atrial fibrillation?
Does aPTT correlate with plasma dabigatran concentration in Japanese patients with non-valvular atrial fibrillation?
aPTT significantly correlates with plasma dabigatran concentrations and can be used as a screening index for excess dabigatran levels in Japanese patients with NVAF.
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aPTT may indicate excess dabigatran in Japanese NVAF patients; leaves open prospective validation before clinical adoption.
Shimomura et al. (2014) studied this question.
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