Key result
Increasing age was associated with a significantly decreasing ratio of plasma NT-proBNP to BNP in children and adolescents with and without congenital heart disease (P<0.001).
Why the study?
Does the ratio of NT-proBNP to BNP change with age in children and adolescents?
Cross-Sectional (n=76)
Does the ratio of NT-proBNP to BNP change with age in children and adolescents?
p-value: p=<0.001
The ratio of NT-proBNP to BNP decreases with increasing age in children and adolescents, highlighting the need for age-specific considerations when interpreting these biomarkers in pediatric cardiology.
No takes yet. Share an insight, caveat, or question.
May require age-adjusted NT-proBNP/BNP interpretation in pediatrics; leaves open validation for diagnostic thresholds.
Koch et al. (2006) conducted a cross-sectional in Congenital heart disease (n=76). Increasing age vs. Younger age was evaluated on Ratio of NT-proBNP to BNP (p=<0.001). Increasing age was associated with a significantly decreasing ratio of plasma NT-proBNP to BNP in children and adolescents with and without congenital heart disease (P<0.001).
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