February 2, 2022Indian Heart JournalOpen Access

The pooled incidence of LTAs was 6.29% (95% CI 4.70-8.08%), and LTAs were associated with significantly increased in-hospital mortality (OR 4.74, 95% CI 2.24-10.04, p<0.0001) and cardiogenic shock (OR 5.60, 95% CI 3.51-8.95, p<0.00001).

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Why the study?

The study was conducted to determine the incidence of life-threatening arrhythmias in patients with Takotsubo cardiomyopathy and evaluate clinical outcomes in patients with versus without life-threatening arrhythmias.

Does the presence of life-threatening arrhythmias increase the risk of mortality and cardiogenic shock in patients with Takotsubo cardiomyopathy?

Comparison

Patients with life-threatening arrhythmias vs those without

Design

Systematic review and meta-analysis

Authors

SRSawai Singh Rathore KIKinza Iqbal SSShameel Shafqat

Discussion

Member takes

Overview

May prompt closer arrhythmia monitoring in Takotsubo cardiomyopathy; extends prior observations with pooled prognostic estimates.

Structured PICO

Does the presence of life-threatening arrhythmias increase the risk of mortality and cardiogenic shock in patients with Takotsubo cardiomyopathy?

Population

18 studies involving 55,557 participants with Takotsubo cardiomyopathy (2,185 with life-threatening arrhythmias and 53,372 without).

Intervention

Presence of life-threatening arrhythmias (LTAs)

Comparator

Absence of life-threatening arrhythmias

Outcome

Incidence of life-threatening arrhythmias in Takotsubo cardiomyopathy patientshard clinical

Life-threatening arrhythmias occur in approximately 6.3% of Takotsubo cardiomyopathy patients and are associated with significantly higher risks of in-hospital mortality and cardiogenic shock.

Cite This Study

Rathore et al. (2022) studied this question.

synapsesocial.com/papers/6a22df7e887b2d65ce606048 https://doi.org/10.1016/j.ihj.2022.01.005

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February 2, 2022Indian Heart JournalOpen Access

The pooled incidence of LTAs was 6.29% (95% CI 4.70-8.08%), and LTAs were associated with significantly increased in-hospital mortality (OR 4.74, 95% CI 2.24-10.04, p<0.0001) and cardiogenic shock (OR 5.60, 95% CI 3.51-8.95, p<0.00001).

View Full Paper

Ask AI

Bookmark

Why the study?

Does the presence of life-threatening arrhythmias increase the risk of mortality and cardiogenic shock in patients with Takotsubo cardiomyopathy?

Comparison

Patients with life-threatening arrhythmias vs those without

Design

Systematic review and meta-analysis

Authors

SRSawai Singh Rathore KIKinza Iqbal SSShameel Shafqat

Discussion

Member takes

Overview

May prompt closer arrhythmia monitoring in Takotsubo cardiomyopathy; extends prior observations with pooled prognostic estimates.

Structured PICO

Does the presence of life-threatening arrhythmias increase the risk of mortality and cardiogenic shock in patients with Takotsubo cardiomyopathy?

Population

18 studies involving 55,557 participants with Takotsubo cardiomyopathy (2,185 with life-threatening arrhythmias and 53,372 without).

Intervention

Presence of life-threatening arrhythmias (LTAs)

Comparator

Absence of life-threatening arrhythmias

Outcome

Incidence of life-threatening arrhythmias in Takotsubo cardiomyopathy patientshard clinical

Life-threatening arrhythmias occur in approximately 6.3% of Takotsubo cardiomyopathy patients and are associated with significantly higher risks of in-hospital mortality and cardiogenic shock.

Cite This Study

Rathore et al. (2022) studied this question.

synapsesocial.com/papers/6a22df7e887b2d65ce606048 https://doi.org/10.1016/j.ihj.2022.01.005

View Full Paper

Ask AI

Bookmark