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April 26, 2017EP Europace

The presence of life-threatening arrhythmias in takotsubo syndrome was associated with significantly higher rates of cardiopulmonary resuscitation (61.5% vs. 1%) and cardiogenic shock (53.8% vs. 14.8%).

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Why the study?

Does the presence of life-threatening arrhythmias worsen clinical outcomes in patients with takotsubo syndrome?

Population

114 patients diagnosed with takotsubo syndrome (TTS) between 2003 and 2015 from an institutional database

Comparison

Presence of life-threatening arrhythmias vs Absence of life-threatening arrhythmias

Design

Cohort

Follow-up

3 years

Key result

The presence of life-threatening arrhythmias in takotsubo syndrome was associated with significantly higher rates of cardiopulmonary resuscitation (61.5% vs. 1%) and cardiogenic shock (53.8% vs. 14.8%).

Authors

IEIbrahim El‐BattrawySLSiegfried LangUAUzair Ansari

Discussion

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Member takes

Overview

LTA in TTS signals higher in-hospital risk; observational data leaves open whether targeted monitoring improves outcomes.

Study Design

Type

Cohort (n=114)

Structured PICO

Does the presence of life-threatening arrhythmias worsen clinical outcomes in patients with takotsubo syndrome?

P
Population
114 patients diagnosed with takotsubo syndrome between 2003 and 2015, followed for 3 years to determine clinical outcomes.
E
Exposure
Presence of life-threatening arrhythmias (LTA) (n=13, 11.4%)
C
Comparator
Absence of life-threatening arrhythmias (n=101, 88.6%)
O
Outcome
Short- and long-term prevalence, recurrence rate, and impact of life-threatening arrhythmias on clinical outcome (including acute cardiovascular events, in-hospital mortality, and overall survival over 3 years)hard clinical

Main Result

Absolute Event Rate: 61.5% vs 1%

Life-threatening arrhythmias in takotsubo syndrome are associated with severe acute in-hospital complications and higher in-hospital mortality, but do not appear to negatively impact long-term 3-year survival.

Cite This Study

El‐Battrawy et al. (2017) conducted a cohort in Takotsubo syndrome (n=114). Presence of life-threatening arrhythmias (LTAs) vs. Absence of LTAs was evaluated on Cardiopulmonary resuscitation. The presence of life-threatening arrhythmias in takotsubo syndrome was associated with significantly higher rates of cardiopulmonary resuscitation (61.5% vs. 1%) and cardiogenic shock (53.8% vs. 14.8%).

synapsesocial.com/papers/6a7b0d458d250a4360f44b92https://doi.org/10.1093/europace/eux073
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