Key result
Percutaneous transmitral commissurotomy and mitral valve replacement acutely improved peak systolic global left atrial strain in patients with severe mitral stenosis (P<0.001 and P=0.012).
Why the study?
Does percutaneous transmitral commissurotomy or mitral valve replacement improve peak atrial longitudinal strain in patients with severe symptomatic mitral stenosis?
Observational
Does percutaneous transmitral commissurotomy or mitral valve replacement improve peak atrial longitudinal strain in patients with severe symptomatic mitral stenosis?
p-value: p=<0.001 and 0.012
Treatment of severe symptomatic mitral stenosis with PTMC or MVR acutely improves left atrial function as measured by peak atrial longitudinal strain.
Acute LA strain gains after PTMC or MVR may support functional benefit; leaves open effects on clinical outcomes in severe mitral stenosis.
AIM: Peak atrial longitudinal strain (PALS) is used to evaluate left atrium (LA) function in patients with mitral stenosis (MS), before and after percutaneous transmitral commissurotomy (PTMC) and mitral valve replacement (MVR). METHODS: Patients with severe symptomatic MS, who were referred to our echocardiographic laboratory for a diagnostic examination before cardiac surgery or PTMC from October of 2014 to October of 2015, were included in the study. RESULT: The peak systolic global LA strain improved post-PTMC (P < 0.001) and post-MVR (P = 0.012). This difference was statistically highly significant. CONCLUSION: PALS is impaired in patients with severe symptomatic MS and improved acutely after treatment and may be a good indicator of LA function and may predict the right time for intervention on mitral valve.
No takes yet. Share an insight, caveat, or question.
Rohani et al. (2017) conducted an observational in Severe symptomatic mitral stenosis. Percutaneous transmitral commissurotomy (PTMC) or mitral valve replacement (MVR) vs. Pre-intervention baseline was evaluated on Peak systolic global left atrial strain (PALS) (p=<0.001 and 0.012). Percutaneous transmitral commissurotomy and mitral valve replacement acutely improved peak systolic global left atrial strain in patients with severe mitral stenosis (P<0.001 and P=0.012).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: