Key result
Calcium channel blockers are effective in lowering blood pressure and reducing cardiovascular morbidity and mortality in elderly patients with hypertension, particularly isolated systolic hypertension.
Why the study?
Do calcium channel blockers reduce cardiovascular morbidity and mortality in elderly patients with hypertension?
Population
Elderly patients with hypertension, including those with isolated systolic hypertension or comorbid…
Comparison
Calcium channel blockers vs Thiazide-type diuretics and…
Design
Review
Authors
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Supports CCBs for elderly hypertension with isolated systolic hypertension; leaves open optimal comparisons with diuretics for heart failure prevention.
Do calcium channel blockers reduce cardiovascular morbidity and mortality in elderly patients with hypertension?
Calcium channel blockers are effective first-line therapies for hypertension in the elderly, particularly for isolated systolic hypertension, though they are less effective than diuretics or ACE inhibitors for preventing heart failure.
Rehman et al. (2005) conducted a review in Hypertension in the elderly. Calcium channel blockers vs. Thiazide-type diuretics and angiotensin-converting enzyme inhibitors was evaluated. Calcium channel blockers are effective in lowering blood pressure and reducing cardiovascular morbidity and mortality in elderly patients with hypertension, particularly isolated systolic hypertension.
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