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August 19, 2008Obesity

Epicardial Adipose Tissue Extent: Relationship With Age, Body Fat Distribution, and Coronaropathy

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Key result

Anterior epicardial adipose tissue surface was positively associated with coronary artery disease (P=0.01), independently of age and other adiposity measurements.

Population

56 cadavers of adult victims of accidental or suspicious sudden death

Design

Cross-sectional

Authors

ASAlina SilaghiInsermMPMarie‐Dominique Piercecchi‐MartiCentre National de la Recherche ScientifiqueMGMichel GrinoInserm

Discussion

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Implication

Anterior EAT-CAD association beyond adiposity warrants prospective validation; leaves open utility for risk stratification.

Study Design

Type

Observational (n=56)

Structured PICO

P
Population
56 adult cadavers of victims of accidental or suspicious sudden death evaluated for epicardial adipose tissue and coronary artery disease.
O
Outcome
Relationship between epicardial adipose tissue (EAT) extent, anthropometric markers of adiposity, presence and staging of coronary artery disease (CAD), and markers of myocardial hypertrophysurrogate

Main Result

Effect estimate: r = 0.38

p-value: p=0.0034

Epicardial adipose tissue extent correlates independently with age, waist circumference, heart weight, and the presence and severity of coronary artery disease.

Cite This Study

Silaghi et al. (2008) conducted an observational in Coronary artery disease (n=56). Epicardial adipose tissue (EAT) extent was evaluated on Presence and staging of coronary artery disease (CAD) (r = 0.38, p=0.0034). Anterior epicardial adipose tissue surface was positively associated with coronary artery disease (P=0.01), independently of age and other adiposity measurements.

synapsesocial.com/papers/6a22fd34d6da8eab4757ec83https://doi.org/10.1038/oby.2008.379

Topics

Coronary artery diseaseCoronary CT angiography
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