Key result
Patients with coronary artery disease had significantly higher epicardial adipose tissue thickness compared to non-CAD patients (SMD 1.07).
Why the study?
The authors sought to systematically evaluate the efficacy and diagnostic value of epicardial adipose tissue in coronary artery disease.
Does epicardial adipose tissue thickness measured by echocardiography or CT correlate with the presence of coronary artery disease?
Population
4049 patients across 21 articles
Comparison
CAD group vs non-CAD group
Design
Meta-analysis
Authors
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Epicardial adipose tissue thickness may aid CAD detection; leaves open its incremental value over standard risk factors.
Meta-Analysis (n=4,049)
Does epicardial adipose tissue thickness measured by echocardiography or CT correlate with the presence of coronary artery disease?
Standardized Mean Difference: 1.07 (95% CI 0.75–1.38)
p-value: p=<0.00001
Epicardial adipose tissue thickness is significantly increased in patients with coronary artery disease, suggesting it may serve as a useful non-invasive imaging biomarker for CAD diagnosis and risk stratification.
Yuan et al. (2019) conducted a meta-analysis in Coronary artery disease (n=4,049). Coronary artery disease (CAD) vs. Without coronary artery disease (non-CAD) was evaluated on Epicardial adipose tissue (EAT) thickness (SMD 1.07, 95% CI 0.75-1.38, p=<0.00001). Patients with coronary artery disease had significantly higher epicardial adipose tissue thickness compared to non-CAD patients (SMD 1.07).
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