Key result
Epicardial adipose tissue thickness was significantly greater in patients with obstructive CAD (8.5 vs 5.4 mm) and independently correlated with its presence (OR 29.16, P<0.001).
Why the study?
Coronary artery disease is a leading cause of death worldwide, but its relationship with epicardial adipose tissue is not yet fully established.
Does epicardial adipose tissue thickness measured by echocardiography correlate with the presence of significant coronary artery disease in patients presenting with chest pain?
Population
100 patients presenting with chest pain undergoing echocardiography and coronary angiography
Comparison
Significant coronary artery stenosis (>70%) vs normal coronary findings
Design
Comparative cross-sectional study
Authors
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EAT thickness by echocardiography may identify CAD in symptomatic patients; hypothesis-generating and should not change practice without prospective validation.
Cross-Sectional (n=100)
Does epicardial adipose tissue thickness measured by echocardiography correlate with the presence of significant coronary artery disease in patients presenting with chest pain?
Odds Ratio: 29.16
Absolute Event Rate: 8.5% vs 5.4%
p-value: p=<0.001
Epicardial adipose tissue thickness ≥6.6 mm measured by echocardiography is strongly associated with the presence of obstructive coronary artery disease in patients with chest pain.
Baraka et al. (2024) conducted a cross-sectional in Coronary artery disease (n=100). Epicardial adipose tissue (EAT) thickness vs. Normal coronary findings was evaluated on Significant coronary artery stenosis (>70%) on angiography (OR 29.16, p=<0.001). Epicardial adipose tissue thickness was significantly greater in patients with obstructive CAD (8.5 vs 5.4 mm) and independently correlated with its presence (OR 29.16, P<0.001).
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