Key result
Increased systolic epicardial adipose tissue thickness was a strong independent predictor of coronary artery disease (OR 7.78) and correlated significantly with angiographic disease severity.
Why the study?
Data linking epicardial adipose tissue to cardiovascular risk and atherosclerotic plaque development were sparse from the Indian subcontinent.
Does epicardial adipose tissue thickness measured by echocardiography predict the presence and severity of coronary artery disease in patients undergoing coronary angiography?
Population
500 patients, including 250 with normal coronaries and 250 with significant CAD on angiogram
Comparison
Significant CAD vs angiographically normal coronary arteries
Design
Cross-sectional observational study
Authors
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May aid noninvasive CAD risk stratification via echo; leaves open incremental value in prospective studies.
Cross-Sectional (n=500)
No
Does epicardial adipose tissue thickness measured by echocardiography predict the presence and severity of coronary artery disease in patients undergoing coronary angiography?
Odds Ratio: 7.78 (95% CI 3.45–10.56)
p-value: p=0.002
Echocardiographic measurement of epicardial adipose tissue thickness is an independent predictor of the presence and severity of coronary artery disease, offering a simple, non-invasive tool for cardiovascular risk assessment.
Verma et al. (2019) conducted a cross-sectional in Coronary artery disease (n=500). Epicardial adipose tissue (EAT) thickness vs. Lower EAT thickness was evaluated on Presence of coronary artery disease (OR 7.78, 95% CI 3.45-10.56, p=0.002). Increased systolic epicardial adipose tissue thickness was a strong independent predictor of coronary artery disease (OR 7.78) and correlated significantly with angiographic disease severity.
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