Key result
An epicardial adipose tissue thickness cutoff of 6.50 mm on echocardiography predicted significant coronary artery disease with an area under the curve of 0.872 (95.6% sensitivity, 77.8% specificity).
Why the study?
Epicardial adipose tissue thickness correlates with abdominal fat and metabolic syndrome, but its correlation with the presence and severity of angiographic coronary artery disease needed evaluation.
Does Epicardial Adipose Tissue Thickness (EATT) predict the presence and severity of angiographic coronary artery disease in patients undergoing coronary angiography?
Cross-Sectional (n=100)
No
Does Epicardial Adipose Tissue Thickness (EATT) predict the presence and severity of angiographic coronary artery disease in patients undergoing coronary angiography?
Effect estimate: AUC 0.872
Epicardial adipose tissue thickness measured by echocardiography can effectively predict the presence of significant coronary artery disease.
Background: Epicardial Adipose Tissue Thickness (EATT) has clinically correlated with abdominal fat and metabolic syndrome. The incidence of CAD is likely to increase further because of rapid urbanisation and its accompanying lifestyle changes, including changes in diet, physical inactivity, drug and alcohol intake, as well as an increase in the prevalence of DM. Objective: To correlate the Epicardial Adipose Tissue Thickness (EATT) to predict presence and severity of angiographic coronary artery disease. Materials & Methods: This was a cross sectional observational study conducted in department of General medicine at Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar, India from March 2019 to March 2020. 100 consecutive patients were enrolled with age more than 18 to 75 years undergoing coronary angiography for this study. Written informed consent was obtained from all the participants. Results: In this study consisting of 100 participants participated in the study having mean age of 56.53 ± 10.46 years. Mean EATT score in obese patients found more which 12.6 with SD of 3.481 compare to Overweight and Normal patients. The cutoff value of EAT on echocardiography to diagnose significant CAD was 6.50 mm on receiver operating characteristic curve analysis with an area under the curve being 0.872 and sensitivity of 95.6% and specificity of 77.8%. Conclusion: Use of EAT thickness measurement in routine practice could be of assistance in identifying patients at risk and guiding them in proper control risk factors and, if required, undergoing evaluations with invasive approaches.
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Sridhar et al. (2021) conducted a cross-sectional in angiographic coronary artery disease (n=100). Epicardial Adipose Tissue Thickness (EATT) was evaluated on presence and severity of angiographic coronary artery disease (AUC 0.872). An epicardial adipose tissue thickness cutoff of 6.50 mm on echocardiography predicted significant coronary artery disease with an area under the curve of 0.872 (95.6% sensitivity, 77.8% specificity).
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