Key result
Adding regional and phase analysis to global ejection fraction determination had limited value in detecting impaired left ventricular function compared to global ejection fraction alone.
Why the study?
Does the addition of regional and phase analysis to global ejection fraction measurement using radionuclide techniques improve the detection of impaired left ventricular function in patients with coronary heart disease?
Cross-Sectional
Does the addition of regional and phase analysis to global ejection fraction measurement using radionuclide techniques improve the detection of impaired left ventricular function in patients with coronary heart disease?
Adding regional and phase analysis to global ejection fraction measurement using radionuclide techniques provides limited additional diagnostic value for detecting impaired left ventricular function in patients with angina or myocardial infarction.
Global EF suffices for LV assessment in CAD; leaves open added value of regional analysis in other modalities or populations.
In order to evaluate the left ventricular function in coronary artery disease, radionuclide measurements of global and regional ejection fraction (EF), regional wall motion and phase analyses of the left ventricular contraction were performed by equilibrium technique. One group of patients with angina pectoris and one group with myocardial infarction were compared with a control group. All the above-mentioned parameters significantly separated the infarction group from the reference group both at rest and during work, while the group of patients with angina pectoris showed disturbances mainly during work, such as impaired ability to increase global and regional ejection fraction and regional wall motion. Adding regional analysis and phase analysis to the global EF determination increases the possibility of studying the left ventricular function. However, this addition has a limited value in detecting impaired left ventricular function compared to the determination of just global EF in patients with angina pectoris and in patients with myocardial infarction.
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Boström et al. (1988) conducted a cross-sectional in Coronary heart disease. Addition of regional and phase analysis to global ejection fraction determination vs. Global ejection fraction alone was evaluated on Left ventricular function parameters (global and regional EF, regional wall motion, phase analyses) at rest and during work. Adding regional and phase analysis to global ejection fraction determination had limited value in detecting impaired left ventricular function compared to global ejection fraction alone.
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