Key result
Targeted ablation guided by the STAR Apollo mapping system successfully terminated persistent atrial fibrillation and maintained sinus rhythm at 5 months without antiarrhythmic medications.
Why the study?
The treatment of persistent atrial fibrillation often requires ablation of additional targets beyond pulmonary vein isolation, motivating novel mapping and ablation approaches.
Case Report (n=1)
No
The STAR Apollo mapping system can successfully identify targetable early sites of activation to achieve acute termination and short-term freedom from persistent atrial fibrillation.
May support STAR Apollo mapping for persistent AF termination; hypothesis-generating and should not yet change practice.
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice.1 It affects close to 6 million individuals in the United States alone.2 AF is considered persistent if it lasts continuously for 7 days and long standing if it lasts for more than 12 months, affecting more than 70% of the total cases.3 The treatment of persistent AF requires ablation of additional targets in conjunction to pulmonary vein isolation (PVI) such as substrate modification, focal ablation of complex fractional atrial electrograms, and a hybrid approach combining epicardial with endocardial ablation.
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Mahtani et al. (2024) conducted a case report in Persistent atrial fibrillation (n=1). STAR Apollo mapping system-guided targeted ablation was evaluated on Termination of atrial fibrillation and maintenance of normal sinus rhythm. Targeted ablation guided by the STAR Apollo mapping system successfully terminated persistent atrial fibrillation and maintained sinus rhythm at 5 months without antiarrhythmic medications.
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