Population
Spontaneously hypertensive rats
Design
Preclinical
Authors
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Hypothesis-generating for baroreflex blunting by arteriosclerosis in hypertension; human studies required before clinical consideration.
In spontaneously hypertensive rats on a high-fat diet, arteriosclerotic lesions increase vascular rigidity and blunt the blood pressure response to sinoaortic denervation.
Myo Thant (1970) studied this question.
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