Key result
Non-contact mapping demonstrated that during sinus rhythm, the human left atrium activates mainly through posterior septal fibers adjacent to the ostia of the right pulmonary veins.
Observational
Non-contact mapping reveals that human left atrial activation during sinus rhythm occurs primarily via posterior septal fibers, suggesting Bachmann's bundle may be less important than previously recognized.
Challenges conventional Bachmann's bundle primacy; leaves open whether posterior septal routes warrant targeted mapping studies.
The pattern of left atrial (LA) activation during sinus rhythm (SR) in humans has not been delineated. The authors used a non-contact mapping system to analyze the patterns of left atrial (LA) activation during sinus rhythm and pacing. The system is capable of simultaneously reproducing more than 3,000 electrograms, which are superimposed on a virtual left atrial endocardium. Data were recorded in sinus rhythm and during pacing from the high right atrium, coronary sinus os, and right atrial septum. The authors demonstrate that during sinus rhythm, the LA activates mainly through posterior septal fibers, adjacent to the ostia of the right pulmonary veins. This suggests that, in humans, anterior interatrial connections including Bachmann's bundle may be less important than previously recognized.
No takes yet. Share an insight, caveat, or question.
Markides et al. (2002) conducted an observational in Sinus rhythm. Non-contact mapping system was evaluated on Patterns of left atrial activation. Non-contact mapping demonstrated that during sinus rhythm, the human left atrium activates mainly through posterior septal fibers adjacent to the ostia of the right pulmonary veins.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: