Key result
Left atrial endocardial mapping in 19 patients showed earliest breakthrough during sinus rhythm occurred more frequently in the septal (63%) than anterosuperior (37%) left atrium.
Population
19 patients undergoing percutaneous noncontact mapping and 10 normal adult postmortem hearts
Design
Cohort
Authors
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May inform septal LA targeting in AF ablation; hypothesis-generating and requires prospective validation.
Observational (n=19)
The left atrial endocardium exhibits complex but characteristic activation patterns determined by the functional properties of atrial musculature, providing anatomical and electrophysiological insights for AF ablation strategies.
Markides et al. (2003) conducted an observational in Atrial fibrillation (n=19). Percutaneous noncontact mapping was evaluated on Left atrial endocardial activation patterns and earliest endocardial breakthrough. Left atrial endocardial mapping in 19 patients showed earliest breakthrough during sinus rhythm occurred more frequently in the septal (63%) than anterosuperior (37%) left atrium.
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