Key result
A modified Miller-Geselowitz heart model successfully simulated the Wolff-Parkinson-White syndrome by specifying eight separate accessory pathway initiation sites to generate preexcitation isochrones.
A modified computational heart model successfully simulates the activation patterns and electrocardiographic features of Wolff-Parkinson-White syndrome.
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Advances WPW preexcitation modeling; extends Miller-Geselowitz framework but leaves open clinical validation.
Lorange et al. (1986) studied Wolff-Parkinson-White preexcitation syndrome. Modified Miller-Geselowitz heart model vs. Original Miller-Geselowitz model was evaluated on Simulation of activation isochrones, body surface potential maps, electrocardiograms, and vectorcardiograms. A modified Miller-Geselowitz heart model successfully simulated the Wolff-Parkinson-White syndrome by specifying eight separate accessory pathway initiation sites to generate preexcitation isochrones.
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