Key result
Migraine was associated with impaired sympathetic function, evidenced by significantly reduced heart rate increases during sustained handgrip compared to healthy volunteers.
Why the study?
Does autonomic nervous system function differ between patients with migraine and healthy controls?
Case-Control (n=107)
Does autonomic nervous system function differ between patients with migraine and healthy controls?
Migraine patients exhibit impaired sympathetic function, evidenced by reduced heart rate responses during sustained handgrip and altered heart rate variability upon standing.
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Supports migraine-sympathovagal imbalance association; hypothesis-generating, should not change practice pending prospective data.
Pogačnik et al. (1993) conducted a case-control in Migraine (n=107). Migraine vs. Healthy volunteers was evaluated on Autonomic nervous system function (including heart rate increases during sustained handgrip). Migraine was associated with impaired sympathetic function, evidenced by significantly reduced heart rate increases during sustained handgrip compared to healthy volunteers.
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