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September 1, 1986Headache The Journal of Head and Face Pain

Autonomic Dysfunction in Adult Migraineurs

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Why the study?

Do adult migraine patients exhibit autonomic dysfunction during headache-free intervals compared to healthy controls?

Population

60 adult migraine patients (aged 23 to 50 years) and 35 healthy control subjects of similar age

Comparison

Assessment of cardiovascular reflexes during… vs Healthy control subjects

Design

Case-control

Authors

HHH. Havanka‐KanniainenOulu University HospitalUTU. TolonenUniversity of Eastern FinlandVMVilho V. MyllyläUniversity of Oulu

Discussion

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Implication

Supports interictal autonomic hypofunction in migraine; hypothesis-generating and requires prospective validation before clinical adoption.

Structured PICO

Do adult migraine patients exhibit autonomic dysfunction during headache-free intervals compared to healthy controls?

P
Population
60 adult migraine patients (aged 23 to 50 years) and 35 healthy control subjects of similar age
I
Intervention
Assessment of cardiovascular reflexes (pulse rate variation and blood pressure reactions) during headache-free intervals
C
Comparator
Healthy control subjects
O
Outcome
Autonomic nervous system function measured by cardiovascular reflexes (pulse rate variation in normal/deep breathing, Valsalva manoeuvre, orthostatic test; blood pressure reactions in orthostatic and isometric work tests)surrogate

Adult migraine patients exhibit mild parasympathetic and definite sympathetic hypofunction during headache-free intervals compared to healthy controls.

Cite This Study

Havanka‐Kanniainen et al. (1986) studied this question.

synapsesocial.com/papers/6a7ea648e7861671be8ec6f9https://doi.org/10.1111/j.1526-4610.1986.hed2608425.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Autonomic Dysfunction in Migraine: A Survey of 188 Patients1988 · 59 citations
  2. 2Cardiovascular Reflexes in Young Migraine Patients1986 · 20 citations
  3. 3Evaluation of Autonomic Dysfunction in Pediatric Migraine Patients2024 · 1 citations
  4. 4Migraine and autonomic nervous system function2002 · 148 citations
  5. 5Autonomic nervous system function in childhood migraine1999 · 33 citations