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August 27, 2024Journal of Dr Behcet Uz Children s HospitalOpen Access

Evaluation of Autonomic Dysfunction in Pediatric Migraine Patients

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Why the study?

Although autonomic nervous system alterations are recognized in adult migraine, few studies have evaluated this relationship in pediatric patients.

Do pediatric migraine patients exhibit autonomic dysfunction compared to healthy children?

Population

Thirty pediatric migraine patients in interictal period and control children without headache or other disease

Comparison

Pediatric migraine patients vs controls without headache or other disease

Design

Case-control study

Authors

DADuygu AykolDokuz Eylül UniversityNDNurhak DemirNear East UniversityAPAyşe PolatDokuz Eylül University

Discussion

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Implication

Autonomic testing in pediatric migraine remains exploratory; larger prospective studies needed before clinical consideration.

Structured PICO

Do pediatric migraine patients exhibit autonomic dysfunction compared to healthy children?

P
Population
30 pediatric migraine patients in interictal period and a control group of healthy children without any other disease or headache
I
Intervention
Autonomic function tests (orthostatic test, 30:15 ratio, cold-pressor test, heart-rate responses to deep and normal breathing, valsalva ratio, blink reflex, and sympathetic skin response)
C
Comparator
Healthy children without any other disease or headache
O
Outcome
Autonomic dysfunction (sympathetic and parasympathetic function)surrogate

Pediatric migraine patients demonstrate autonomic dysfunction, characterized by decreased sympathetic responsiveness and parasympathetic hyperfunction during the interictal period.

Cite This Study

Aykol et al. (2024) studied this question.

synapsesocial.com/papers/6a6ff5f378a11c550e09bf2bhttps://doi.org/10.4274/jbuch.galenos.2024.28159
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Autonomic nervous system function in childhood migraine1999 · 33 citations
  2. 2Autonomic Dysfunction in Adult Migraineurs1986 · 54 citations
  3. 3Autonomic Function Testing in Patients with Migraine1993 · 81 citations
  4. 4Autonomic Nervous System Function in Migraine Without Aura1991 · 60 citations
  5. 5Heart Rate Recovery in Migraine and Tension‐Type Headache2007 · 32 citations